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Mavacamten（Cat No.:I007910）is a selective cardiac myosin inhibitor designed to treat hypertrophic cardiomyopathy (HCM). By targeting excessive myosin activity, it reduces abnormal heart muscle contraction, relieving symptoms such as shortness of breath, chest pain, and fatigue.
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90
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MyoKardia
cardiac myosin inhibitor Cardiac Myosin Inhibitor, supplied by MyoKardia, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/myk+461/myk+461/pm35538236-1-4-14 Average 90 stars, based on 1 article reviews
cardiac myosin inhibitor - by Bioz Stars,
2026-09
90/100 stars
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90
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ApexBio
myk- 461 Myk 461, supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/myk+461/myk++461/10__1096_slash_fj__202002111rr-31-0-5 Average 90 stars, based on 1 article reviews
myk- 461 - by Bioz Stars,
2026-09
90/100 stars
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MYK 461 is an orally bioavailable inhibitor of cardiac myosin ATPase IC 0 3 µM in purified bovine myosin S1 It is selective for cardiac myosin over skeletal myosin IC 4 7 µM and does
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MYK-461 is a myosin inhibitor that selectively decreases the ATPase activity of cardiac myosin heavy chain, thus it is potentially for the treatment of hypertrophic cardiomyopathy (HCM).
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InformationMavacamten (MYK-461) Mavacamten (MYK-461, SAR439152) is a small-molecule modulator of cardiac myosin that targets the underlying sarcomere hypercontractility of hypertrophic cardiomyopathy (HCM), one of the most prevalent heritable cardiovascular disorders.In vitroMYK-461 primarily reduces the steady-state
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